FIELD: bioengineering.
SUBSTANCE: claimed invention discloses the immunoconjugate for effector fragment delivery to influence cells activity. The said immunoconjugate comprises one single chain effector fragment and two antigen-binding fragments that represent a Fab molecule. Besides, this invention discloses the molecules of nucleic acids, encoding immunoconjugates, vectors and host cells containing the nucleic acid molecules, production of the said immunoconjugates described hereby and application thereof for disease treatment.
EFFECT: perfected properties.
133 cl, 53 dwg, 23 tbl, 28 ex
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Authors
Dates
2016-05-10—Published
2010-08-13—Filed