IMMUNOCONJUGATES OF DIRECTIVE EFFECT Russian patent published in 2016 - IPC C07K16/46 A61K39/395 

Abstract RU 2583876 C2

FIELD: bioengineering.

SUBSTANCE: claimed invention discloses the immunoconjugate for effector fragment delivery to influence cells activity. The said immunoconjugate comprises one single chain effector fragment and two antigen-binding fragments that represent a Fab molecule. Besides, this invention discloses the molecules of nucleic acids, encoding immunoconjugates, vectors and host cells containing the nucleic acid molecules, production of the said immunoconjugates described hereby and application thereof for disease treatment.

EFFECT: perfected properties.

133 cl, 53 dwg, 23 tbl, 28 ex

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RU 2 583 876 C2

Authors

Ralf Khosse

Ekkekhard Messner

Mikela Silachchi-Melkko

Pablo Umana

Dates

2016-05-10Published

2010-08-13Filed