FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and medicine, specifically to production of liquid stable shigella serum, which can be used for putting passive hemagglutination reaction (PHR), as well as in agglutination reaction (AR). Invention can also be used for producing a kit for detection of specific antibodies to various kinds of shigella in human blood serum in passive hemagglutination reaction (PHR). Invention represents a method of producing a stable liquid serum of diagnostic shigella, having ability to preserve functional activity of antibodies with their long-term stay in aqueous solutions using polyglucin and krashemodez, diagnostic shigella serum obtained using said method and kit for detection of specific antibodies to various kinds of shigella in blood serum, including said serum.
EFFECT: invention allows at any time to have ready to use of serum, decreases consumption of materials used, eliminates steps of producing labour-intensive and energy-consuming freeze drying stage, which considerably simplifies process of producing serum.
5 cl, 1 tbl
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RU2584596C1 |
METHOD OF INFECTIONS IMMUNODIAGNOSIS | 0 |
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METHOD OF IMMUNODIAGNOSIS | 0 |
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RU2305842C1 |
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|
RU2136000C1 |
METHOD FOR SELECTING PERSONS TO VACCINATE THEM AGAINST DIPHTHERIA AND TETANUS INFECTION | 0 |
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SU1720006A1 |
METHOD OF DETERMINING ANTIVIRUS ANTIBODIES | 0 |
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SU1571506A1 |
METHOD FOR OBTAINING BRUCELLOSIS DIAGNOSTIC KIT | 2004 |
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RU2269360C2 |
Authors
Dates
2016-05-20—Published
2015-06-05—Filed