METHOD OF IMMUNODIAGNOSIS OF INFECTIONS Russian patent published in 1999 - IPC

FIELD: medicine. SUBSTANCE: method is based on detection of erythrocytes from specific and nonspecific erythrocyte diagnostica in adhesion smears by lymphocytes and neutrophils. Method involves simultaneous determination in patient blood with respect of each diagnosticum species an amount of erythrocytes adhesized by rosette-forming leukocytes and leukocytes adhesized 1-2 erythrocytes. Index of specific adhesion is measured by the formula: index = (ΣPO_sp/ΣPO_nonsp)/(ΣA_sp(1+2)/ΣA_nonsp(1+2)) where ΣPO_sp and PO_nonsp - sum of erythrocytes of specific and nonspecific erythrocyte diagnostica, respectively, adhesized by rosette-forming leukocytes; and ΣA_sp(1+2) and ΣA_nonsp(1+2) - sum of adhesion of erythrocytes from specific and nonspecific diagnostica, respectively, for leukocytes adhesized 1-2 erythrocytes. Infection is diagnosed at index value above 1.8 and below 0.4. Method can be used for early immunodiagnosis of infections. EFFECT: simplified method of diagnosis. 4 tbl, 3 ex