AGENT WITH LIPOSOMES CONTAINING NICOTINIC ACID AND PROPOLIS EXTRACT HAVING DETOXIFICATION AND ANTIOXIDANT ACTIVITY Russian patent published in 2016 - IPC A61K31/455 A61K35/644 A61K9/127 A61K9/48 A61P39/06 

Abstract RU 2585099 C1

FIELD: chemistry.

SUBSTANCE: invention relates to an agent possessing detoxification and antioxidant activity. Agent contains nicotinic acid and 10% alcohol extract of propolis, included in liposomes. Said liposomes are obtained by mixing at 40°C egg lecithin and cholesterol, taken in ratio 1:0.2, followed by hydrating with solution of sucrose. Liposomes are enclosed in capsules for oral administration in following ratio of components of liposomes per 1 capsule: 0.2 g nicotinic acid, 0.2 g of 10 % alcohol extract of propolis, 0.22 g of mixture of lecithin and cholesterol 1:0.2, hydrated with 0.5 % sucrose solution.

EFFECT: invention is characterised by high bioavailability and marked prolonged action, providing maximum delivery of active substances of gastrointestinal tract in blood flow.

3 cl, 5 tbl, 7 ex

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RU 2 585 099 C1

Authors

Shikova Yuliya Vitalevna

Simonyan Elena Vladimirovna

Likhoded Vitalij Alekseevich

Yumaguzhina Alina Timeryanovna

Abramovskikh Kseniya Alekseevna

Bakhtiyarova Svetlana Bikmukhametovna

Dates

2016-05-27Published

2014-12-22Filed