CRYSTALLINE FORMS OF SODIUM SALT OF 5-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE, PHARMACEUTICAL PREPARATIONS CONTAINING SAME AND METHODS OF PRODUCING SAID FORMS Russian patent published in 2016 - IPC C07D237/32 A61K31/502 A61P37/02 

Abstract RU 2585677 C2

FIELD: chemistry.

SUBSTANCE: claim describes two new crystalline forms I and II of 5-amino-2,3-dihydrophthalazine-1,4-dionata sodium salt, which have values of crystallographic characteristics determined by means of x-ray images, given in claim. Invention also describes methods of said crystalline forms producing. Produced forms I and II have different immunological effects. Besides, both forms possess useful physical and chemical properties, which can be used for producing, processing and/or application for pharmaceutical production form I or form II, or their mixture.

EFFECT: this useful characteristic applicable for immune-specific purposes.

11 cl, 4 dwg, 13 tbl, 3 ex

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RU 2 585 677 C2

Authors

Jozef Broj

Volfgang Brish

Astrid Kajzer

Beate Ludesher

Gerrit Mass

Tomas Martin

Volfgang Milius

Mikhael Nidermajer

Dates

2016-06-10Published

2011-03-01Filed