PHARMACEUTICAL COMPOSITIONS FOR INHIBITING INFLAMMATORY CYTOKINES Russian patent published in 2024 - IPC C07K5/10 A61K38/07 A61P37/00 A61P1/00 A61P11/00 A61P27/00 

Abstract RU 2816868 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and represents the use of a pharmaceutical composition containing, as an active ingredient, a peptide selected from a group consisting of pGlu-Asn-Trp-Lys(octanoyl)-OH (SEQ ID NO: 1), pGlu-Asn-Trp-Thr-OH (SEQ ID NO: 2) and pharmaceutically acceptable salts thereof, for the treatment of an inflammatory disease or disorder selected from the group consisting of an inflammatory disease or disorder of the eye, inflammatory disease or disorder of ear, inflammatory disease or disorder of lungs, inflammatory disease or disorder of intestine, or inflammatory autoimmune disease or disorder.

EFFECT: invention provides attenuation of expression of inflammatory and pro-inflammatory mediators by peptides designated ZEP3 and ZEP4.

16 cl, 17 dwg, 9 tbl, 15 ex

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RU 2 816 868 C2

Authors

Primor, Naftali

Dates

2024-04-08Published

2019-03-28Filed