DRUG PREPARATION WITH HEPATOPROTECTIVE ACTIVITY Russian patent published in 2016 - IPC A61K31/513 A61P1/16 

FIELD: pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents a drug preparation with hepatoprotective activity, which is a 3-(4-bromophenyl)-6,6-dihydroxy-5-hydroxyiminohexahydro-2,4-pyrimidinedione and its salts of general formula:

where X is selected from: H, Na, K, or from a group hydroxyalkylammonium derivatives of general formula

where R1, R2 are selected from: H, CH₃, CH₂CH₃, CH₂CH₂OH; R3 is selected from: H, CH₂OH; n = 1, 2.

EFFECT: higher efficiency of medicinal agent with hepatoprotective activity combined with lower toxicity.

8 cl, 4 ex, 17 tbl