ANTIBODIES AGAINST TNF-α AND USE THEREOF Russian patent published in 2016 - IPC C07K16/24 C12N15/13 A61K39/395 A61P1/04 A61P1/06 A61P19/02 A61P37/00 A61P19/04 

Abstract RU 2595379 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry, particularly to an anti-TNF(tumour necrosis factor)-α antibody or anti-TNF-α-binding fragment antibody. Also disclosed is a pharmaceutical composition for treating pathologies and diseases associated with TNF-α, containing a therapeutically effective amount of said antibody or fragment thereof.

EFFECT: invention provides effective treatment of TNF-α-mediated disease.

15 cl, 6 dwg, 25 tbl, 2 ex

Similar patents RU2595379C2

Title Year Author Number
ANTI-VEGF ANTIBODIES AND APPLICATIONS THEREOF 2010
  • Harding Fiona A.
  • Akamatsu Yoshiko
  • Dubridge Robert B.
  • Powers David B.
RU2567639C2
RECOVERED HUMAN ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT (VERSIONS), METHOD OF TREATING hTNFα-MEDIATED DISEASES WITH MEDIATION THEREOF (VERSIONS), PHARMACEUTICAL COMPOSITION, RECOMBINANT HUMAN ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT, RECOVERED NUCLEIC ACID (VERSIONS) 2005
  • Allen Debora Dzh.
  • Vogen Tristan Dzh.
  • Kajmaksalan Zera
  • Labkovski Boris
  • Makginess Brajen T.
  • Mankovich Dzhon Eh.
  • Roberts Ehndrju Dzh.
  • Sakorafash Pol'
  • Sehlfeld Dzhokhen G.
  • Uajt Majkl
  • Uilton Ehlison Dzh.
  • Khugenbum Khendrikus R. Dzh. M.
  • Shoehnkhaut Dehvid
RU2458704C9
METHOD AND OBTAINED HUMAN ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT FOR INHIBITING HUMAN TNF ACTIVITY, APPLYING THE OBTAINED HUMAN ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT AS INGREDIENT FOR PRODUCING MEDICAMENT 1997
  • Allen Debora Dzh.
  • Vogen Tristan Dzh.
  • Kajmaksalan Zera
  • Makginess Brajen T.
  • Mankovich Dzhon Eh.
  • Roberts Ehndrju Dzh.
  • Sakorafash Pol'
  • Sehlfeld Dzhokhen G.
  • Uajt Majkl
  • Uilton Ehlison Dzh.
  • Khugenbum Khendrikus R. Dzh. M.
  • Shoehnkhaut Dehvid
  • Labkovski Boris
RU2270030C2
METHOD OF TREATING VISCERAL PAIN BY ADMINISTERING ANTAGONIST ANTIBODIES AGAINST CALCITONIN GENE-RELATED PEPTIDE 2010
  • Pios Ariel Ates
  • Polsen Kristian Todd
  • Shelton David Louis
  • Zeller Joerg
RU2535074C2
ANTIBODIES WITH PH-DEPENDENT ANTIGEN BINDING 2011
  • Pons Dzhom
  • Chehbot Dzheffri Rehjmond
  • Chaparro Ridzhers Khav'Er Fernando
  • Gomes Brjus Charl'Z
  • Ljan Khon
  • Majavala Kapil
  • Mettetal' Vtoroj Dzherom Tomas
  • Radzhpal Arvind
  • Shelton Dehvid L'Juis
RU2570729C2
TREATMENT OF INTERSTITIAL CYSTITIS 2008
  • Millz Ajan Uill'Jam
  • Rozental' Arnon
  • Sholfild Dehvid Piter
  • Shelton Dehvid L'Juis
  • Fillips Stefen Charl'Z
RU2570559C2
METHODS FOR IDENTIFYING ANTIBODIES WITH REDUCED IMMUNOGENICITY 2013
  • Harding Fiona A.
  • Razo Olivia Jennifer
RU2648141C2
METHODS OF OSTEOARTHRITIS PAIN MANAGEMENT BY ADMINISTRATION OF NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING IT 2006
  • Rozental' Arnon
  • Shelton Dehvid L.
  • Uolik Patritsija Ehnn
RU2429013C2
ISOLATED HUMAN ANTIBODY OR ITS ANTIGEN-BINDING FRAGMENT, ISOLATED NUCLEIC ACID (VARIANTS), RECOMBINANT EXPRESSION VECTOR, USING HOST-CELLS FOR EXPRESSION OF ANTIBODY AND METHOD FOR ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITION OF ACTIVITY OF HUMAN TNFα 1997
  • Allen Debora Dzh.
  • Vogen Tristan Dzh.
  • Kajmaksalan Zera
  • Makginess Brajen T.
  • Mankovich Dzhon Eh.
  • Roberts Ehndrju Dzh
  • Sakorafash Pol'
  • Sehlfeld Dzhokhen G.
  • Uajt Majkl
  • Uilton Ehlison Dzh.
  • Khugenbum Khendrikus R. Dzh. M.
  • Shoehnkhaut Dehvid
  • Labkovski Boris
RU2268266C2
IMPROVED AMINO ACID SEQUENCES AGAINST IL-6R AND POLYPEPTIDES WHICH CONTAIN THEREOF FOR TREATMENT OF IL-6R ASSOCIATED DISEASES AND DISORDERS 2010
  • Bajrnaehrt, Ehl'S, Anna, Ehllis
  • Ververken, Sedrik, Jozef, Neotere
  • Kolkman, Jost, Aleksander
  • Van Roj, Marten
RU2539798C2

RU 2 595 379 C2

Authors

Harding Fiona A.

Akamatsu Yoshiko

Dubridge Robert B.

Powers David B.

Dates

2016-08-27Published

2010-04-16Filed