N-ALKYL-TROPINES AND N-ALKYL-NORTROPINES HAVING h-LYTIC, ANTIPARKINSONIAN, ANTIEPILEPTIC, ANALGESIC AND ANTIDEPRESSANT ACTIVITY Russian patent published in 2016 - IPC A61K31/46 A61P25/08 A61P25/16 A61P25/24 A61P25/04 C07D451/02

Abstract RU 2597616 C2

FIELD: chemistry.

SUBSTANCE: invention relates to use of N-alkyl derivatives of tropine and nortropine of general formula (I) for treating Parkinson's disease, epilepsy, depression and pain. Invention also relates to a method of treating Parkinson's disease, epilepsy, depression and pain.

EFFECT: technical result is compounds of formula (I) have considerable advantages over mecamylamine, since they considerably surpass mecamylamine on H-cholinolytic, antiparkinsonian, antidepressant and analgesic activity.

3 cl, 12 tbl

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RU 2 597 616 C2

Authors

Gmiro Valerij Evgenevich

Shabanov Petr Dmitrievich

Serdyuk Sergej Evgenevich

Dates

2016-09-10—Published

2014-11-05—Filed