FIELD: chemistry.
SUBSTANCE: invention relates to novel crystalline form (2R, 3S, 5R) -2-(2,5diftorphenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-yl]tetrahydro-2H-pyran-3-amine compound I characterized by the presence of at least four peaks in its X-ray diffraction on powders selected from the series consisting of 10.3+0.1 2θ, 12.7±0.1 2θ, 14.6±0.1 2θ, 16.1±0.1 2θ, 17.8±0.1 2θ, 19.2±0.1 2θ, 22.2±0.1 2θ, 24.1±0.1 2θ and 26.9±0.1 2θ, which is a potent inhibitor of dipeptidylpeptidase-IV.
EFFECT: invention also relates to the usage of this compound in treating of insulin-independent diabetes (Type 2), as well as to pharmaceutical compositions based thereon.
12 cl, 16 dwg, 6 tbl
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