COMPOUNDS AND COMPOSITIONS USED FOR TREATMENT OF NTRK-RELATED DISORDERS Russian patent published in 2021 - IPC C07D487/04 A61K31/519 A61P35/00 

Abstract RU 2744974 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to novel inhibitors of neurotrophic receptor tyrosine kinase (NRTK), to a pharmaceutical composition, and to a method for treating a subject with a condition mediated by aberrant NRTK activity.

EFFECT: novel NRTK inhibitors are proposed that can be used in tumor treatment.

8 cl, 1 dwg, 1 tbl, 29 ex

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RU 2 744 974 C2

Authors

Wenglowsky Steven Mark

Brooijmans Natasja

Miduturu Chandrasekhar V.

Bifulco Neil

Dates

2021-03-17Published

2016-08-25Filed