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(19)

(11)

2 707 292

(13)

(51)

IPC

C07D513/04(2006-01-01)

C07H9/06(2006-01-01)

A61K31/429(2006-01-01)

A61K31/7056(2006-01-01)

A61P25/28(2006-01-01)

A61P35/00(2006-01-01)

A61P27/06(2006-01-01)

(21) (22)

Application

2014149183, 2013-05-03

(24)

Start date

2013-05-03

(22)

Actual filing date

2013-05-03

(45)

Published

2019-11-26

(72)

Inventor

Selnik Kharold Dzh.Li VenpinKhostetler ErikLyu KunMakichern Ernest Dzh.Chzhou YuansiVej ChzhunyunMu ChanvejVan YaodeChan Tszian

(73)

Holder

Merk Sharp I Doum Korp.Alektos Terapyutiks Ink.

PERMEABLE GLYCOSIDASE INHIBITORS AND USE THEREOF Russian patent published in 2019 - IPC C07D513/04 C07H9/06 A61K31/429 A61K31/7056 A61P25/28 A61P35/00 A61P27/06

Abstract RU 2707292 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to compounds and their pharmaceutically acceptable salts, which are disclosed in the patent claim.

EFFECT: compounds of the invention are useful as inhibitors of O-linked N-acetylglucosaminidase (O-GlcNAc-daza) and can be useful for treating certain disorders, such as Alzheimer's disease.

7 cl, 4 tbl, 120 ex

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RU 2 707 292 C2

Authors

Selnik Kharold Dzh.

Li Venpin

Khostetler Erik

Lyu Kun

Makichern Ernest Dzh.

Chzhou Yuansi

Vej Chzhunyun

Mu Chanvej

Van Yaode

Chan Tszian

Dates

2019-11-26—Published

2013-05-03—Filed