FIELD: medicine.
SUBSTANCE: present invention relates to use of a gel composition, comprising melatonin or a derivative thereof in a proportion of 2.5 % to 5 % w/v for treating and/or preventing mucositis, said gel composition is locally administered in the mucosal surface. Mucositis is preferably caused by radiotherapy and/or chemotherapy, and is preferably oral mucositis.
EFFECT: technical result is lower level oxidative stress in mitochondria, that ensures complete prevention of stomatitis.
12 cl, 17 dwg
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