FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental medicine, and can be used for preventing radiation oral mucositis in mice. Method comprises the preventive intragastric administration to an animal of a compound T1082 dissolved in water, in dose of 1/10-1/15 LD10, 30 minutes before a single local radiation exposure β-radiation to the head and neck region in dose of 18 Gy.
EFFECT: using the invention enables eliminating the intraoperative lethality of laboratory animals during the procedure, while obtaining a complete, verifiable and reproducible model of severe oral mucositis.
1 cl, 4 dwg, 3 tbl, 4 ex
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