COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARISATION AND RELATED DISEASES Russian patent published in 2016 - IPC A61K31/433 A61P9/00 A61P27/00 

Abstract RU 2600794 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to ophthalmology, and can be used for preparing a drug for treating diabetic macular oedema, wherein compound is 4-{(S)-2-[(S)-2-(methoxycarbonylamino)-3-phenylpropaneamido]-2-[2-(thiophen-2-yl)thiazol-4-yl]ethyl}phenylsulphamic acid or pharmaceutically acceptable salt thereof. Invention also discloses use of compound for preparing a drug for prevention of diabetic macular oedema and pharmaceutical composition for treating diabetic macular oedema.

EFFECT: group of inventions provides treatment of eye diseases or conditions, in particular retinopathy, ocular edema and ocular neovascularisation, in such eye diseases as: diabetic macular oedema, age-related macular degeneration (wet form), choroidal neovascularisation, diabetic retinopathy, retinal vein occlusion (central or branch), ocular trauma, surgery induced edema, surgery induced neovascularisation, cystoid macular edema, ocular ischemia, uveitis.

6 cl, 13 dwg, 21 tbl, 24 ex

Similar patents RU2600794C2

Title Year Author Number
COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTION OF METASTATIC CANCER CELLS 2010
  • Shalvits Robert
  • Peters Kevin Dzhin
RU2519123C2
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND APPLICATION METHODS THEREOF 2007
  • Grehj Dzheffri Lajl
  • Amarasige Kande
  • Klark Sintija Moneza
  • Majer Meht'Ju Brajan
  • Nikols Rajan
RU2435763C2
METHOD OF TREATING VASCULAR LEAK SYNDROME 2010
  • Shalvits Robert
  • Peters Kevin Dzhin
RU2539917C2
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USING SAID INHIBITORS 2007
  • Grehj Dzheffri Lajl
  • Amarasinge Kande
  • Klark Sintija Moneza
  • Majer Meht'Ju Brajan
  • Nikols Rajan
RU2447065C2
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND APPLICATION METHOD THEREOF 2007
  • Grehj Dzheffri Lajl
  • Amarasinge Kande
  • Klark Sintija Moneza
  • Majer Meht'Ju Brajan
  • Nikols Rajan
RU2430101C2
NOVEL 1,2-BIS-SULPHONAMIDE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR 2011
  • Yuan Khajtsin
  • Bird Richard L.
  • Lyu Syaosya
  • Donello Dzhon E.
  • Visvanat Veena
  • Garst Majkl E.
RU2654213C9
FLUORINATED COMPOUND OF CYCLOPROPYLAMINE, THE METHOD OF PREPARATION, THE PHARMACEUTICAL COMPOSITION AND ITS USE 2017
  • Liu, Khong
  • Li, Dzhia
  • Vang, Dzhiang
  • Su, Mingbo
  • Vang, Skhuni
  • Zkhou, Yuubo
  • Zkhu, Vei
  • Ksyu, Vei
  • Li, Kkhunpu
  • Dzhiang, Khualiang
  • Chen, Kaiksian
RU2746323C2
THIAZOL DERIVATIVE AND USING IT AS VAP-1 INHIBITOR 2009
  • Matsukava Tatsuja
  • Masuzaki Kazukhiro
  • Kavai Josuke
  • Kavasaki Akiko
  • Akasaka Akiko
  • Takevaki Makoto
RU2496776C9
ARYLCARBONYL DERIVATIVES AS THERAPEUTIC AGENTS 2003
  • Polizetti Dkharma Rao
  • Kodra Janos Tibor
  • Lau Jesper
  • Blok Pav
  • Val'Karse-Lopes Marija Karmen
  • Blume Nil'S
  • Guzel' Mustafa
  • Santosh Kalpati Chidambaresvaran
  • Mdzhalli Adnan M. M.
  • Ehndrjus Robert Karl
  • Subramanian Govindan
  • Ankersen Mikhael'
  • Vedse Per
  • Mjurrehj Ehntoni
  • Jeppesen Lone
  • Lau Jesper
RU2340605C2
ARYL- AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF FOR INHIBITING NOREPINEPHRINE, DOPAMINE AND SEROTONIN REUPTAKE 2005
  • Molino Brjus F.
  • Lju Shuan
  • Berkovits Behrri A.
  • Gazzo Piter R.
  • Bek Dzhejms P.
  • Kokhen Marlin
RU2388751C2

RU 2 600 794 C2

Authors

Peters Kevin Dzh.

Shalvitz Robert

Dates

2016-10-27Published

2011-10-05Filed