FIELD: medicine.
SUBSTANCE: claimed group of inventions relates to medicine, namely to therapy and haematology and deals with treatment of increased vascular permeability (vascular leak syndrome). For this purpose effective amount of compound, which has formula: , is introduced.
EFFECT: introduction of claimed compound under control of angiopoetin-2 level provides recovery of vascular wall integrity in case of various diseases, accompanied by increased vascular permeability, due to inhibition of proteintyrosinephosphatase-beta (PTP-β).
21 cl, 24 ex, 20 tbl, 10 dwg
Title | Year | Author | Number |
---|---|---|---|
COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTION OF METASTATIC CANCER CELLS | 2010 |
|
RU2519123C2 |
COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARISATION AND RELATED DISEASES | 2011 |
|
RU2600794C2 |
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND APPLICATION METHODS THEREOF | 2007 |
|
RU2435763C2 |
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USING SAID INHIBITORS | 2007 |
|
RU2447065C2 |
HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND APPLICATION METHOD THEREOF | 2007 |
|
RU2430101C2 |
AMINOPYRIMIDINE DERIVATIVES AND USE THEREOF AS AROMATIC HYDROCARBON RECEPTOR MODULATORS | 2021 |
|
RU2826628C1 |
PHENOXYPHENYL ACETIC ACID | 1994 |
|
RU2139273C1 |
GLYCOLATOXIDASE INHIBITORS FOR THE TREATMENT OF DISEASES | 2018 |
|
RU2805308C2 |
SELECTIVE GLYCOSIDASE INHIBITORS AND USE THEREOF | 2011 |
|
RU2609210C2 |
MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | 2014 |
|
RU2678327C2 |
Authors
Dates
2015-01-27—Published
2010-01-12—Filed