FIELD: medicine.
SUBSTANCE: group of inventions relates to methods and compositions for inhibiting the contraction of muscles and, in particular, to methods and compositions for inhibiting the contraction of smooth muscles of the urinary bladder. For this purpose, in production of a medicinal agent a pharmaceutical composition containing a first agent is used, namely, acetaminophen in an amount of 5 mg to 2,000 mg, and the second agent which is selected from a group consisting of an antimuscarinic agent, an antidiuretic and a spasmolysant. Besides, in production of a medicinal agent a pharmaceutical composition is used, containing the first component configured to fast release, and the second component configured for prolonged release, where each of said components contains acetaminophen in an amount of 5 mg to 2,000 mg. Pharmaceutical composition for prolonged release is also disclosed, containing acetaminophen in a dose of 5 mg to 2,000 mg, an antidiuretic and a pharmaceutically acceptable carrier.
EFFECT: group of inventions provides the effective suppression of smooth muscle contraction of the bladder.
28 cl, 9 tbl, 8 ex, 1 dwg
Authors
Dates
2016-11-27—Published
2012-08-22—Filed