FIELD: medicine, anesthesiology, biochemistry, pharmacy.
SUBSTANCE: invention relates to methods for pain treatment. Invention proposes a pharmaceutical composition containing cyclooxygenase-2 inhibitor and opioid analgetic. This allows reducing the plasma concentration of opioid analgetic in retaining the effective pain elimination and diminishing adverse effects of treatment.
EFFECT: enhanced and valuable medicinal properties of combination.
12 cl, 3 dwg, 2 tbl, 2 ex
Authors
Dates
2004-07-20—Published
1998-09-17—Filed