FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to neonatology, and can be used for prediction of lethal outcome in premature newborns in cerebral ischemia caused by congenital cytomegalovirus infection. Method of determining pH in aspirate from anterior nasal cavity (A), pH in aspirate from deep-lying portion nasopharyngeal space (B) and activity of lactate dehydrogenase in aspirate from anterior nasal cavity (Un/l) (C). Then by means of discriminant equation, including defined properties, predicting lethal outcome in premature newborns in cerebral ischemia: D=-58.953×A+87.849×B-0.004×C, where D is discriminant function with boundary value equal to +194.71. If D is equal to or greater than limit value of discriminant function, absence of fatal outcome in cerebral ischemia is predicted, and if D is less than limit value, lethal outcome in cerebral ischemia of average degree of severity is predicted, caused by congenital cytomegalovirus infection in premature newborns. Probability of correct prediction is 80.3 %.
EFFECT: invention provides early performance of therapeutic measures aiming at prevention of fatal outcome in given category of patients.
1 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| EARLY DIAGNOSTIC TECHNIQUE FOR VENTRICULOMEGALIA ACCOMPANYING MODERATE CEREBRAL ISCHEMIA IN NEWBORNS SUFFERING INTRAUTERINE CYTOMEGALOVIRAL INFECTION | 2013 |
|
RU2546010C1 |
| EARLY DIAGNOSTIC TECHNIQUE FOR VENTRICULOMEGALIA ACCOMPANYING SEVERE CEREBRAL ISCHEMIA IN NEW-BORNS WITH INTRAUTERINE CYTOMEGALOVIRUS-HERPETIC INFECTION | 2013 |
|
RU2542429C1 |
| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR GENERALISED FORM OF INTRAUTERINE MONO- AND MIXED CYTOMEGALOVIRUS INFECTION IN NEWBORNS | 2013 |
|
RU2553632C1 |
| METHOD OF PREDICTING LETHAL OUTCOME ON NEWBORN BABIES IN CASE OF CEREBRAL ISCHEMIA OF SEVERE DEGREE | 2012 |
|
RU2492488C1 |
| METHOD OF EARLY DIAGNOSTICS OF INFLAMMATORY DISEASES OF BRAIN AND ITS MENINGES IN TERM NEWBORNS WITH INTRAUTERINE CYTOMEGALOVIRUS-HERPES INFECTION | 2014 |
|
RU2563132C1 |
| METHOD FOR PREDICTION OF LETHAL OUTCOME IN HYPERTENSIVE HYDROCEPHALUS SYNDROME IN FULL-TERM NEWBORNS WITH CONGENITAL CYTOMEGALOVIRUS INFECTION | 2019 |
|
RU2707184C1 |
| EARLY DIAGNOSTIC TECHNIQUE FOR CEREBRAL ISCHEMIA OF VARIOUS SEVERITIES IN NEWBORNS | 2008 |
|
RU2372620C1 |
| DIAGNOSTICS METHOD FOR RESPIRATORY DISTRESS SYNDROME IN NEWBORN | 2007 |
|
RU2342667C1 |
| METHOD OF PRE-CLINIC DIAGNOSTICS OF SEVERITY DEGREE OF RESPIRATORY DISTRESS-SYNDROME IN CASE OF INTRAUTERINE INFLUENZA A (H3N2) IN PREMATURE INFANTS | 2012 |
|
RU2492489C1 |
| METHOD FOR PREDICTION OF ADVERSE PERINATAL OUTCOMES WITH FETAL GROWTH RETARDATION SYNDROME IN WOMEN WITH REACTIVATION OF CHRONIC CYTOMEGALOVIRUS INFECTION IN SECOND TRIMESTER OF PREGNANCY COMPLICATED BY RETROPLACENTARY HEMATOMA | 2016 |
|
RU2648472C1 |
