ENCAPSULATED DOSAGE FORM, CONTAINING MONTELUKAST AND LEVOCETIRIZINE Russian patent published in 2017 - IPC A61K9/48 A61K31/47 A61P11/02 A61K31/4704 

FIELD: pharmaceutics.

SUBSTANCE: invention relates to capsule dosage form for preventing or treating allergic rhinitis and asthma, which consists of two separate layers: (1) montelukast layer, containing montelukast or its pharmaceutically acceptable salt; and (2) levocetirizine layer, containing levocetirizine or its pharmaceutically acceptable salt, in which said montelukast layer and levocetirizine layer contain water in amount of 5 % and less; and their production method.

EFFECT: encapsulated dosage form, according to invention, can completely separate two active ingredients, minimizing so reaction activity between them and improving stability of product with respect to ageing effect and thus optimizing therapeutic action.

20 cl, 5 tbl, 9 ex