DEVICE FOR PREPARATION OF DRY THERMOLABILE BIOLOGICAL MATERIALS Russian patent published in 2017 - IPC F26B11/14 

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, namely to production of biomass for preparation of dry powder forms of immunobiological preparations, in particular drying (dehydration) of liquid thermolabile biologically active materials in multi-component mixture, their grinding and mixing till formation of homogeneous mass, and can be used in pharmaceutical industry for production of powders and tableted drugs for preventing and treating infectious diseases in human and animals. In case of device there is neck with rotary perforated damper, which combines functions of material loading and unloading. On neck of device case there is retainer with wedge-like locks for tight connection to expander-trap, intended for connection to vacuum system, and to catch particles of dried material and return them to working zone of device. Device is installed horizontally on support frame, design of which provides possibility of rotation of device case relative to horizontal axis through 180° and fixing its position with upper and lower orientation of the neck consequently. Cooling water jacket covers 3/4 of working side surface of cylindrical case of device. Device allows to perform in one cycle drying of thermolabile biological material under vacuum conditions at optimum temperature conditions and observing aseptic measures of process and preparation of homogeneous powdered mass by mixing obtained dry material with components of filler.

EFFECT: technical result of invention is creation of tightly closed device design combining functions of drier and mixer-grinder, which makes it possible to intensify process of drying of liquid thermolabile biological materials, reducing their thermal inactivation and probability of contamination of external microbiological flora.

1 cl, 1 dwg