FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry, particularly to an antibody which specifically binds with CAPRIN-1 protein and having immunological reactivity with respect to a partial polypeptide of CAPRIN-1 protein, wherein said antibody has cytotoxic activity against a cancer cell expressing CAPRIN-1 protein, as well as a medicinal agent containing same. Invention also relates to a method of treating or preventing CAPRIN-1 expressing cancer using said antibody or composition.
EFFECT: invention provides effective treatment or prevention of CAPRIN-1 expressing cancer.
17 cl, 3 dwg, 6 ex
