FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to laboratory diagnostics, and can be used for assessing body reaction of an experimental animal on the introduction of a synthetic mesh implant. For this purpose, frozen in cryostat fragment of the implant is refined with the help of microtome to particles with size less than 10 mcm. Then dried, sterilized, re-suspended in a sterile physiologic saline and administered intraperitoneally for small laboratory animals using a syringe. Examine the values of functional activity of peritoneal macrophages for evaluation of local reaction.
EFFECT: using the given method allows studying of reaction of the experimental animal's body to the introduction of synthetic mesh implant for evaluating of biocompatibility of the synthetic mesh implants used in pelvic prolapse correction and hernia repair of anterior abdominal wall of stomach.
1 cl, 2 ex, 1 dwg, 1 tbl
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Authors
Dates
2017-01-10—Published
2015-04-29—Filed