FIELD: pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics. Described is an aqueous composition for injections containing the suspension of 10–20 wt%. of buprenorphine particles in water solution; polyethylene glycol polymer with the molecular weight of 3350, nonionic surfactant. Said composition contains buprenorphine particles with average particle size less than 20 µm and does not contain polylactide or polyglycolide polymer or their mixture. Also described is a method of treating the opioid addiction or pain relief with the said composition.
EFFECT: invention provides prolonged release of buprenorphine within 7–30 days.
17 cl, 4 dwg, 8 tbl, 5 ex
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