FIELD: medicine.
SUBSTANCE: invention relates to experimental biology and medicine and can be used for prevention of anthrasilicosis. The method includes modelling of disease by daily poisoning of experimental animals with coal-rock dust with simultaneous application of preventive medication. As such preparation biologically active additive Cyto-Reactor dihydroquercetin is introduced into animal diet in dose 3 mg/kg of animal body weight. Duration of the experiment constitutes 12 weeks.
EFFECT: method ensures reduction of expression of dystrophic and sclerotic changes in tissues, normalisation of parts of lipid metabolism, including ratios of blood lipoproteids, as well as general metabolism due to elongation of phase of long-term adaptation.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| NEW COMPLEX OF BIOLOGICALLY ACTIVE COMPOUNDS OUT OF LARCH BARK NAMED PICNOLAR | 2003 |
|
RU2252028C2 |
| METHOD FOR DISLIPIDEMIA PREVENTION | 2016 |
|
RU2621152C1 |
| METHOD OF PREVENTION OF CHRONIC FLUORINE INTOXICATION IN EXPERIMENT SIMULATION | 2018 |
|
RU2673488C1 |
| METHOD FOR SIMULATING ANTHRACOSILICOSIS | 2013 |
|
RU2534872C1 |
| METHOD TO INOCULATE LABORATORY ANIMALS BY INDUSTRIAL DUST FOR SILICOSIS SIMULATION | 2013 |
|
RU2546096C1 |
| HEPATOPROTECTOR PREPARATION FOR PROPHYLAXIS AND CORRECTION OF TOXIC HEPATIC LESIONS | 2001 |
|
RU2189817C1 |
| PHARMACEUTICAL POSSESSING HYPOLIDEMIC, HEPATOPROTECTIVE AND ANTIOXIDANT ACTION | 2016 |
|
RU2636817C2 |
| NUTRITIONAL COMPOSITION | 2017 |
|
RU2654868C1 |
| METHOD OF TREATING ISCHEMIC HEPATIC INJURIES | 2014 |
|
RU2563796C1 |
| PHARMACOLOGICAL INJECTION FOR THE TREATMENT AND PREVENTION OF LIVER DISEASES IN ANIMALS | 2022 |
|
RU2786655C1 |
