FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and medical equipment and can be used for delivery of the composition in an olfactory region of the nasal cavity. Proposed device, comprising a container, diffuser, chamber for composition and nozzle. Container contains a propellant. Diffuser is connected with container and with a chamber for the composition. Nozzle is communicated with chamber for the composition. Disclosed a method using said device for delivery of the composition in an olfactory region of the nasal cavity.
EFFECT: invention provides efficient introduction of composition in an olfactory region and its delivery through the blood-brain barrier due to improvement of the delivery mechanism of most part of the atomized drug in the upper part of the nasal cavity to increase exposure in the olfactory epithelium.
33 cl, 25 dwg, 4 tbl, 5 ex
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Authors
Dates
2017-03-09—Published
2012-03-05—Filed