THERAPEUTIC AGENTS FOR REGULATING SERUM PHOSPHORUS LEVEL Russian patent published in 2017 - IPC A61K38/08 A61P13/12 

Abstract RU 2612912 C2

FIELD: chemistry.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents a method of treating chronic kidney disease-mineral and bone disorder (CKD-MBD) in a patient receiving hemodialysis, wherein said method involves administering to patient a composition containing a compound, including Ac-c(C)arrrar-NH2 (SEQ ID NO: 3), and a pharmaceutically acceptable excipient, where composition is administered as intravenous injection during a period beginning approximately 15 minutes before completion of haemodialysis and ending approximately 3 hours after hemodialysis, and where said administering allows to efficiently maintain post-hemodialysis serum phosphorus level below serum phosphorus level prior to hemodialysis during a period, of at least approximately 6 hours after dialysis.

EFFECT: invention allows to mitigate post-dialysis rebound of serum phosphorus level.

7 cl, 3 dwg, 4 tbl, 2 ex

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Authors

Dates

2017-03-13Published

2012-06-08Filed