METHOD FOR DONOR CORNEA PROCESSING WITH DOUBLE-SIDED UV CROSSLINKING FOR KERATOPROSTHETICS OF COMPLICATED VASCULAR LEUCOMAS OF CATEGORY 4-5 Russian patent published in 2017 - IPC A61F2/14 A61F9/08 A61N5/06 A61K31/525 A61K31/721 A61K33/14 A61K38/06 A61P41/00 

Abstract RU 2613442 C1

FIELD: medicine.

SUBSTANCE: donor cornea is placed in a preserving environment for 1 hour. Then the donor cornea is moved into a sterile container and treated with ultraviolet light from one side of the cornea with a wavelength of 365 nm, power of 3 mW/sq. cm. Instillation of 1 drop of 0.1% riboflavin solution (first processing on cornea is performed very 5 minutes. After processing, the donor cornea is treated with ultraviolet light from the opposite side similarly to the first treatment. The preserving environment contains riboflavin mononucleotide, dextran, glutathione, sodium chloride and purified distilled water, in the following ratio, wt %: riboflavin mononucleotide - 0.1, dextran - 10.0, glutathione - 0.09, sodium chloride - 0. 9, purified distilled water - the rest.

EFFECT: obtaining of donor cornea with increased biochemical, biomechanical and strength properties, thereby reducing the risk of cornea necrosis.

2 cl, 1 ex

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Authors

Dates

2017-03-16Published

2016-04-28Filed