METHOD OF TREATMENT OF KERATECTASIA BY THE METHOD OF PULSE ACCELERATED ULTRAVIOLET CROSSLINKING OF CORNEA Russian patent published in 2019 - IPC A61N5/06 A61K31/525 A61K31/721 A61P27/02 A61M35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used for the treatment of advanced keratectasia. To do this, within 30 minutes carry out the saturation of the corneal stroma with an aqueous solution containing riboflavin. Use an aqueous solution containing Riboflavin, of the following composition, wt. %: Riboflavin mononucleotide 0.14–0.15; dextran 18.0–22.0; tris-(hydroxymethyl)-methylamine 0.08–0.12; Nipagin 0.0075–0.0125; Trilon B 0.005–0.01; sodium chloride 0.8–0.9 and purified distilled water to 100. Perform accelerated ultraviolet irradiation of the cornea with a power density of 18 mW/cm². Irradiation is carried out in a pulsed mode: 1 second light / 1 second pause, lasting 10 minutes. During irradiation, instillations are carried out with the same aqueous solution containing riboflavin at intervals of 1 drop in 1 minute.

EFFECT: method provides an effective and safe procedure, reducing postoperative cross-linking-induced complications (haze), reducing the cost of a photosensitizing solution during instillations.

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