FIELD: medicine.
SUBSTANCE: method is based on DQ2 and DQ8 genes detection, assessment of the specific antibodies level and intestinal atrophy extent. The occurrence frequency of 0201 allel in the DQ locus is determined, at the occurrence frequency from 2 to 3, development of severe Gee's disease with intestinal atrophy Marsh III is predicted.
EFFECT: method is simple, informative and highly reproducible for determination of genetic predisposition to more severe Gee's disease, it allows effective prediction of Gee's disease extent, which provides indication of the possible mucosa recovery terms.
3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIAGNOSING AUTOIMMUNE GASTRITIS IN CHILDREN WITH CELIAC DISEASE | 2020 |
|
RU2759342C1 |
| METHOD OF ASSESSING COMPLIANCE WITH A GLUTEN-FREE DIET IN PATIENTS WITH GLUTEN-SENSITIVE CELIAC DISEASE | 2022 |
|
RU2800820C1 |
| PROBIOTIC COMPOSITIONS AND THEIR APPLICATION | 2018 |
|
RU2763311C2 |
| METHOD OF DETECTING PREDISPOSITION AND RESISTANCE TO DEVELOPMENT OF CYST ECHINOCOCCOSIS IN CHILDREN | 2008 |
|
RU2387383C1 |
| METHODS AND DEVICE FOR GLUTEN SENSITIVITY DETECTION AND ITS DIFFERENTIATION WITH CELIAC DISEASE | 2012 |
|
RU2635516C2 |
| METHOD FOR GENETIC PREDICTION OF RESPIRATORY TUBERCULOSIS | 2009 |
|
RU2406447C2 |
| METHOD FOR PREDICTION OF POLLEN BRONCHIAL ASTHMA | 2010 |
|
RU2441242C1 |
| METHOD OF DETERMINING CLINICAL COURSE DIRECTION OF PATHOLOGICAL PROCESS OF CELIAC DISEASE IN CHILDREN | 2010 |
|
RU2425375C1 |
| METHOD OF PREDICTING SERIOUS COURSES OF LEPROTIC POLYNEURITES | 2007 |
|
RU2350955C1 |
| METHOD FOR PREDICTING THE SEVERITY DEGREE OF CHORIORETINITIS FLOW | 2005 |
|
RU2287822C1 |
