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2 614 734

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(51)

IPC

A61K9/51(2006-01-01)

A61K31/505(2006-01-01)

B01J13/06(2006-01-01)

B82B3/00(2006-01-01)

(21) (22)

Application

2015119280, 2015-05-21

(24)

Start date

2015-05-21

(22)

Actual filing date

2015-05-21

(45)

Published

2017-03-28

(72)

Inventor

Denisyuk Tatyana AlekseevnaKrolevets Aleksandr AleksandrovichSaroyan Karen VanushovichSitnik Mikhail VladimirovichLosenok Polina IgorevnaPokrovskij Mikhail VladimirovichBogachev Ilya AleksandrovichAvtina Valentina ValerevnaGrigorenko Aleksandr Petrovich

(73)

Holder

METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN CARRAGEENAN Russian patent published in 2017 - IPC A61K9/51 A61K31/505 B01J13/06 B82B3/00

Abstract RU 2614734 C2

FIELD: nanotechnology.

SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a suspension of carrageenan in hexane, in presence of 0.005 g of an E472c preparation with mixing at 1,000 rpm, with weight ratio shell: nucleus 3:1 or 1:5, then adding 5 ml of 1,2-dichloroethane; prepared suspension is filtered and dried at room temperature.

EFFECT: invention provides a simpler and faster process of producing nanocapsules, reduces loss during production (higher weight yield).

1 cl, 3 ex, 1 dwg

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RU 2 614 734 C2

Authors

Denisyuk Tatyana Alekseevna

Krolevets Aleksandr Aleksandrovich

Saroyan Karen Vanushovich

Sitnik Mikhail Vladimirovich

Losenok Polina Igorevna

Pokrovskij Mikhail Vladimirovich

Bogachev Ilya Aleksandrovich

Avtina Valentina Valerevna

Grigorenko Aleksandr Petrovich

Dates

2017-03-28—Published

2015-05-21—Filed