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2 605 846

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(51)

IPC

A61K9/51(2006-01-01)

A61K31/505(2006-01-01)

B01J13/06(2006-01-01)

B82B3/00(2006-01-01)

(21) (22)

Application

2015118758/15, 2015-05-19

(24)

Start date

2015-05-19

(22)

Actual filing date

2015-05-19

(45)

Published

2016-12-27

(72)

Inventor

Denisjuk Tatjana AlekseevnaKrolevets Aleksandr AleksandrovichSarojan Karen VanushovichSitnik Mikhail VladimirovichLosenok Polina IgorevnaPokrovskij Mikhail VladimirovichBogachev Ilja AleksandrovichAvtina Valentina ValerevnaGrigorenko Aleksandr Petrovich

(73)

Holder

METHOD OF PRODUCING NANOCAPSULES OF ROSUVASTATIN IN SODIUM ALGINATE Russian patent published in 2016 - IPC A61K9/51 A61K31/505 B01J13/06 B82B3/00

Abstract RU 2605846 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing nanocapsules of rosuvastatin, characterised by that rosuvastatin is slowly added to a sodium alginate suspension in hexane, in presence of 0.005 g of E472c preparation while stirring at 1,000 rpm, at a weight ratio shell:core of 3:1 or 1:5, then adding petroleum ether as a precipitant, obtained suspension is filtered and dried at room temperature.

EFFECT: invention simplifies and speeds up process of producing nanocapsules, reduces loss during production (higher weight yield).

1 cl, 3 ex, 1 dwg

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RU 2 605 846 C2

Authors

Denisjuk Tatjana Alekseevna

Krolevets Aleksandr Aleksandrovich

Sarojan Karen Vanushovich

Sitnik Mikhail Vladimirovich

Losenok Polina Igorevna

Pokrovskij Mikhail Vladimirovich

Bogachev Ilja Aleksandrovich

Avtina Valentina Valerevna

Grigorenko Aleksandr Petrovich

Dates

2016-12-27—Published

2015-05-19—Filed