METHOD OF OBTAINING ROSUVASTATINE NANOCAPSULES IN SODIUM ALGINATE Russian patent published in 2017 - IPC A61K31/505 A61K47/36 A61K9/51 A61J3/07 B01J13/02 B82B3/00 

Abstract RU 2615366 C1

FIELD: nanotechnology.

SUBSTANCE: method of obtaining the rosuvastatine nanocapsules is carried out as follows. Rosuvastatine is slowly added to the suspension of sodium alginate in hexane in the presence of 0.005 g of E472s drug, with stirring at 1000 rpm/sec. Then 3 ml of butyl chloride are poured. The resulting suspension is filtered and dried at the room temperature. The ratio of rosuvastatine: sodium alginate is 1:3 or 5:1.

EFFECT: method as per the invention provides the simplification and acceleration of the nanocapsules obtaining process and the yield increase by weight.

1 dwg, 3 ex

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RU 2 615 366 C1

Authors

Krolevets Aleksandr Aleksandrovich

Dates

2017-04-04Published

2016-05-10Filed