METHOD FOR PREDICTION OF RECURRENT EPISODES OF ACUTE RESPIRATORY VIRAL INFECTIONS FOR PRESCHOOL CHILDREN WITH BRONCHIAL ASTHMA Russian patent published in 2017 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention can be used to predict recurrent episodes of acute respiratory viral infections (ARI) for preschool children with bronchial asthma (BA). History, clinical and laboratory risk factors are determined: absence of acute respiratory virus infection (ARI) for more than one month - x₁; eosinophils level of in complete blood count (CBC) - x₂; actual BA exacerbations against ARI for the last month - x₃; mother's burdened obstetrical history (BOH) - x₄; actual chlamydia and mycoplasma infection in history according to the enzyme-linked blood immunoassay (blood ELISA) - x₅; altered level of natural killer cells (NK cells) - x₆; age at first visit to the children's pre-school institution (CPI) over three years - x₇; altered level of B-lymphocytes - x₈; altered level of immunoglobulin G (IgG) - x₉; age of broncho-obstructive syndrome (BOS) debut - x₁₀; altered level of tumor necrosis factor (TNF) - x₁₁; altered level of interferon-gamma (INF-γ) - x₁₂; altered level of phagocytic activity of monocytes - x₁₃; prophylactic administration of antiviral drugs in the season of increased the ARI incidence - x₁₄. At that, the risk factors x_1, x₃-x₅, x_7, x₁₀, x₁₄ are assigned the value of 1. Risk factors x₂, x_6, x_8, x₉, x₁₁-x₁₃ are assign a value, determined in laboratory tests. Then F is calculated by the formula. If F> 0, a high risk of ARI is predicted. If F <0, a minimal risk of acute respiratory viral infections for children with BA is predicted.

EFFECT: method allows to predict ARI for children with BA with high probability and efficiency, to carry out preventive and rehabilitative measures in a timely manner by evaluating the most significant risk factors.

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