METHOD FOR DIFFERENTIAL DIAGNOSIS OF VARIOUS TYPES OF INTRAHEPATIC CHOLESTASIS FOR CHILDREN Russian patent published in 2017 - IPC G01N33/50 

Abstract RU 2615358 C1

FIELD: medicine.

SUBSTANCE: hepatobiliary scintigraphy is performed using Bromezid 99Tm 38 radiopharmaceutical, administered drug activity is based on 1.7-2.0 MBq per 1 kg of patient weight, intravenously, radiation exposure of 7.0 mGy (700 mrad), and the following is evaluated: maximum accumulation time (Tmax) of the radiopharmaceutical (RP), its half-life (T1/2), time it enters the intestine (Tint). Based on these data, various types of intrahepatic cholestasis (sine and ductular) are differentiated.

EFFECT: method allows timely diagnosis and in some cases, helps to avoid the need for liver biopsy.

2 dwg, 1 tbl, 2 ex

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RU 2 615 358 C1

Authors

Baranov Aleksandr Aleksandrovich

Namazova-Baranova Lejla Sejmurovna

Volynets Galina Vasilevna

Smirnov Ivan Evgenevich

Potapov Aleksandr Sergeevich

Nikitin Artem Vyacheslavovich

Skvortsova Tamara Andreevna

Komarova Nadezhda Lvovna

Dates

2017-04-04Published

2016-02-26Filed