METHOD FOR DETERMINATION OF FEASIBILITY OF IMMUNOLOGICAL STUDY IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE Russian patent published in 2017 - IPC G01N33/48 

Abstract RU 2617236 C1

FIELD: medicine.

SUBSTANCE: invention is intended to determine the feasibility of immunological study for patients with nonalcoholic fatty liver disease (NAFLD). For NAFLD patients, a complete blood count is performed and leukocytic indices are evaluated, including a neutrophil/lymphocyte ratio (NLR) and a granulocyte/lymphocyte ratio (GLR). A polymerase chain reaction is carried out, consisting in colon microorganisms DNA identification in patient's feces, as well as yeast fungi of Candida genus. At the increased value of GLR and reduced value of NLR, respectively, compared with the reference values, as well as reduced amount of Faecalibacterium prausnitzii microorganisms and increased amount of Klebsiella, Enterobacter, Proteus, Citrobacter microorganisms and yeast fungi of Candida genus, immunological study of pations of this category is determined feasible.

EFFECT: method simplifies survey conducted to select the drug therapy.

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RU 2 617 236 C1

Authors

Khurtsilava Otari Givievich

Prikhodko Egor Mikhajlovich

Seliverstov Pavel Vasilevich

Radchenko Valerij Grigorevich

Sitkin Stanislav Igorevich

Smolyaninov Aleksandr Borisovich

Adylov Sherzot Farkhatovich

Yurkevich Yurij Vasilevich

Dates

2017-04-24Published

2015-12-02Filed