FIELD: manufacturing technology.
SUBSTANCE: group of inventions relates to methods for production of hydrogels. According to present invention, disclosed is a method of producing polymer hydrogel, comprising steps of: preparing aqueous solution of water-soluble derivative of polysaccharide and polycarboxylic acid; mixing solution, for example by stirring; extraction of composite derivative of polysaccharide/polycarboxylic acid from solution and heating composite derivative of polysaccharide/polycarboxylic acid at a temperature of about 80°C to allow cross-linking of polysaccharide polycarboxylic acid. Present invention also discloses polymer hydrogels, obtained using methods according to present invention, use of polymer hydrogels as a pharmaceutical composition, medicinal agent for reducing calorie intake, treating obesity, improving glycemic control, agent for preventing diabetes.
EFFECT: group of inventions enables to produce hydrogels having improved sorption properties, furthermore, polymer hydrogels are relatively dense, but retain significant ability to absorb mixture of artificial gastric juice with water.
29 cl, 20 tbl, 12 ex, 13 dwg
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Authors
Dates
2017-05-03—Published
2012-06-07—Filed