COMPOSITIONS AND METHODS FOR TREATMENT OR PREVENTION OF DISORDERS RELATED TO INTESTINAL PERMEABILITY Russian patent published in 2022 - IPC A61K31/717 A61K47/38 A61K9/06 A61P1/04 A61P1/00 

Abstract RU 2782530 C2

FIELD: medicine.

SUBSTANCE: method for prevention or treatment of a non-alcoholic fatty liver disease or non-alcoholic steatohepatitis in a subject who needs it is proposed, including administration to the gastrointestinal tract of the subject of therapeutically effective amount of crosslinked polysaccharide with an elasticity module (G') from 500 Pa to 10,000 Pa.

EFFECT: method provides for increase in the content of mucin in tissues of the gastrointestinal tract and increase in dense compound protein ZO-1 in tissues of the colon, as well as regeneration of intestine tissues.

14 cl, 19 dwg, 2 tbl, 6 ex

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RU 2 782 530 C2

Authors

Demitri Kristian

Sannino Alessandro

Restsigno, Mariya

Zokhar, Jishai

Chikuette, Elejn

Silvestri, Alessandra

Dates

2022-10-28Published

2018-04-16Filed