FIELD: biotechnology.
SUBSTANCE: invention describes jointly-used antimicrobial combinations of bisphosphonates and carbapenems against carbapenem-resistant gram-negative Pseudomonas aeruginosa ATCC 27853 bacteria, producing β metal-lactamase. Antimicrobial combination are characterized by the weight ratio of components, namely of a combination of imipenem/clodronic acid, meropenem/clodronic acid, imipenem/etidronic acid, meropenem/etidronic acid are used in ratios of 1:469, 1:3750, 1:25000, 1:25000, respectively.
EFFECT: possibility of application to overcome resistance to carbapenems in gram-negative Pseudomonas aeruginosa ATCC 27853 bacteria.
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Authors
Dates
2017-05-03—Published
2015-08-10—Filed