FIELD: medicine, pharmacy.
SUBSTANCE: invention includes an antifungal azole pharmaceutical agent - itraconazole or posaconazole, and a solvent, wherein the said solvent comprises a) an alcohol selected from benzyl alcohol and/or acidified ethanol and b) polyethylene glycol (PEG), at that, the azole agent is dissolved in the said solvent, wherein the composition is substantially free of nonionic surfactants and contains less than 5% of water. The invention also refers to the method for preparation of such a composition and its application for medicament preparation and the method for treatment of a patient with a disease responsive to an azole antifungal pharmaceutical agent comprising parenterally injection of a therapeutically effective volume of such composition to a patient.
EFFECT: invention relates to a pharmaceutical composition suitable for parenteral injection.
35 cl, 21 dwg, 11 tbl, 3 ex
| Title | Year | Author | Number |
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RU2760681C2 |
