FIELD: pharmaceuticals.
SUBSTANCE: invention relates to pharmaceutical compositions containing particles produced by spray drying of 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidine-2-yl)piperazine-1-yl)phenyl)-2-oxacetamide particles, as well as an application of the pharmaceutical compositions for prevention or treatment of a fungal infection.
EFFECT: pharmaceutical compositions based on 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidine-2-yl)piperazine-1-yl)phenyl)-2-oxacetamide exhibiting antifungal properties are produced.
30 cl, 3 dwg, 1 tbl, 5 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIFUNGAL AGENTS | 2015 |
|
RU2727520C2 |
PHARMACEUTICAL COMPOSITION OF PYRAZOLE COMPOUND DISPERSED IN POLYMER MATRIX | 2020 |
|
RU2826604C1 |
COMBINED VORICONASOL AND ANTIMYCOTIC INHIBITOR CYP2C19 | 2005 |
|
RU2345769C2 |
METHODS OF TREATING FUNGAL INFECTIONS | 2019 |
|
RU2820457C2 |
(1,10b-DIHYDRO-2-(AMINOALKYLPHENYL)-5H-PYRAZOLO[1,5-c][1,3] BENZOXAZIN-5-YL) PHENYLMETHANONE DERIVATIVES AS HIV VIRAL REPLICATION INHIBITORS | 2006 |
|
RU2416615C2 |
TOSYLATE SALT OF THERAPEUTIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 2008 |
|
RU2430099C2 |
PHARMACEUTICAL COMPOSITIONS | 1996 |
|
RU2159107C2 |
HIV-INHIBITING 2-(4-CYANOPHENYLAMINO)-PYRIMIDINE-OXIDE DERIVATIVES | 2006 |
|
RU2398768C2 |
AMINO ACID ESTERS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1998 |
|
RU2197489C2 |
GRANULE, A METHOD OF ITS PREPARING AND A PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2125445C1 |
Authors
Dates
2021-11-29—Published
2017-05-25—Filed