FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to pharmaceutics, specifically to an extrudate of a mixture of sodium mycophenolate, polyvinylpyrrolidone and polyethylene glycol for making an oral solid dosage form, which is obtained at extrusion temperature of 60–140 °C, wherein sodium mycophenolate is in crystalline form; use of said extrudate for preparing an oral solid dosage form and an oral solid dosage form having an immunosuppressive action containing said extrudate.
EFFECT: group of inventions ensures preservation of crystallinity of sodium mycophenolate after extrusion.
5 cl, 3 dwg, 1 tbl, 24 ex
