CHRONIC TRAUMATIC OSTEOMYELITIS SIMULATION METHOD Russian patent published in 2017 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: to simulate traumatic osteomyelitis of long bones in aseptic conditions, a cavity is created in the metaepiphyseal area of the laboratory animal bone under anesthesia. A turunda moistened with 1% Aethoxysklerol solution and fragments of autologous bone are placed into this cavity, with subsequent cavity infection with the Staphylococcus aureus culture. Infection is performed on day 7 by introduction of a piece of an overnight Staphylococcus aureus culture in 2% solution of agar-agar into the resulting cavity. At that, the hole in the bone is sealed by ercodont cement, and the wound is poured by amoxiclav powder.

EFFECT: method provides simulation of a long, rapidly flowing osteomyelitic process, accompanied by fistulas, and the ability to maintain it for such a long time, which is necessary for the study and objective evaluation of the process using the means and methods of its treatment.