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2 623 034

(13)

(51)

IPC

A61K31/205(2006-01-01)

A61P35/00(2006-01-01)

A61P35/04(2006-01-01)

(21) (22)

Application

2016131263, 2016-07-28

(24)

Start date

2016-07-28

(22)

Actual filing date

2016-07-28

(45)

Published

2017-06-21

(72)

Inventor

Adamovich Sergej NikolaevichMirskova Anna NikolaevnaKolesnikova Olga Petrovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Irkutskij Institut Khimii Im. A.E. Favorskogo Sibirskogo Otdeleniya Rossijskoj Akademii Nauk

ANTINEOPLASTIC AGENT Russian patent published in 2017 - IPC A61K31/205 A61P35/00 A61P35/04

Abstract RU 2623034 C1

FIELD: pharmacology.

SUBSTANCE: suggested: 2-methylphenoxyacetate N-methyl-bis-(2-hydroxyethyl)ammonium (Bikrezan) of the formula [CH₃N(CH₂CH₂OH)₂H]⁺⋅^-OOCCH₂OC₆H₄-CH₃-2 application as an antineoplastic and antimetastatic means. Technical result: the antitumor effect of Bikrezan is shown in vivo on an example of melanoma and hepatoma; the antimetastatic effect of Bikrezan exceeds the cisplatin effect, while Bikrezan is safe - it has no toxic properties.

EFFECT: invention expands the arsenal of funds for the intended purpose, exceeding the therapeutic effect of other anti-cancer drugs.

4 tbl, 4 ex

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RU 2 623 034 C1

Authors

Adamovich Sergej Nikolaevich

Mirskova Anna Nikolaevna

Kolesnikova Olga Petrovna

Dates

2017-06-21—Published

2016-07-28—Filed