FIELD: biotechnology.
SUBSTANCE: antigen-binding fragments (Fab) are described that selectively bind to botulinum neurotoxin C, in particular humanized Fab. Yeast cells producing the said humanized Fab are presented. A method for producing the described humanized Fab is proposed. A method for botulinum neurotoxin C detection and a kit for botulinum neurotoxin C detection is also proposed.
EFFECT: invention allows to obtain reagents for botulinum neurotoxin C detection, which have a high binding specificity to the said neurotoxin.
9 cl, 12 dwg, 6 tbl, 9 ex
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Authors
Dates
2017-06-22—Published
2016-03-15—Filed