ANTIGEN BINDING SECTION (FAB), INCLUDING HUMANIZED FAB, AGAINST BOTULINICAL NEUROTOXIN C (VERSIONS), METHOD TO OBTAIN FAB USING YEAST, METHOD AND SET FOR BOTULINICAL NEUROTOXIN C DETECTION Russian patent published in 2017 - IPC C07K16/12 C12N15/13 C12N15/63 G01N33/53 

Abstract RU 2623157 C1

FIELD: biotechnology.

SUBSTANCE: antigen-binding fragments (Fab) are described that selectively bind to botulinum neurotoxin C, in particular humanized Fab. Yeast cells producing the said humanized Fab are presented. A method for producing the described humanized Fab is proposed. A method for botulinum neurotoxin C detection and a kit for botulinum neurotoxin C detection is also proposed.

EFFECT: invention allows to obtain reagents for botulinum neurotoxin C detection, which have a high binding specificity to the said neurotoxin.

9 cl, 12 dwg, 6 tbl, 9 ex

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RU 2 623 157 C1

Authors

Benevolenskij Sergej Vladimirovich

Bokov Maksim Nikolaevich

Zatsepin Sergej Sergeevich

Klyachko Elena Vitalevna

Pozdnyakova Lyubov Petrovna

Sveshnikov Petr Georgievich

Solopova Olga Nikolaevna

Chulkin Andrej Mikhajlovich

Dates

2017-06-22Published

2016-03-15Filed