METHOD OF OBTAINING SURFACE-ACTIVE SUBSTANCES BASED ON N-ACYLAMINE ACID WITH THE USE OF SURFACE-ACTIVE SUBSTANCES BASED ON N-ACYLAMINE ACID OR THE RELEVANT ANHYDRIDE AS CATALYSTS Russian patent published in 2017 - IPC C07C231/02 C07C233/47 C07C303/22 C07C303/26 C07C309/15 C07C309/69 C07C51/60 C07C53/42 

FIELD: chemistry.

SUBSTANCE: invention relates to a process of preparation based on N-acyl amino acid surfactants of formula I, wherein R is selected from C₆-C₂₂alkyl group, R₁ is selected from H_, C₁-C₄alkyl, R₂ selected from all groups in αcarbon atom of natural amino acids except of functional groups -NH₂ and -COOH, R₃ selected from SOOH, CH₂-SO₃X, i.e., a residue selected from non-naturally occurring amino acids: aminopropionic acid, N-methyl taurine and sarcosine, and X is selected from Li⁺, Na⁺ or K⁺. The method comprises the steps of A) and B). In step A) the preparation of chlorides of fatty acids is carried out by halogenation with thionyl fatty acids in the presence of catalytic amounts of the same or different based on the N-acylamino acid surfactant of formula I or anhydrides surfactant of formula II, wherein R represents C₆-C₂₂alkyl group, R₁ represents H, C₁-C₄alkyl, R₂ represents all groups with αcarbon atom of natural amino acids except of functional groups -NH₂ and -COOH, n is from 0 to 4, X represents C, SO. In step B) the reaction of fatty acid chloride is carried out from step (A) with an amino acid in the presence of aqueous base at conditions of Schotten-Baumann while maintaining the pH of 10 to 11 and a temperature from 20 to 45°C.

EFFECT: method avoids the additional purification steps.

6 cl, 16 tbl, 8 ex