METHOD OF CONVERTING PRIMARY AMIDE ALCOHOLS TO AMIDE CARBOXYLIC ACIDS WITH HIGH OUTPUT USING WATER AS SOLVENT Russian patent published in 2012 - IPC C07C231/12 C07C233/47 

FIELD: chemistry.

SUBSTANCE: method of converting alcohol containing an amide group into the corresponding carboxylic acid involves reaction of a primary amide alcohol of formula: R¹-CONR²(CH₂)_mOH, where R¹ is a linear or branched alkyl or alkenyl group, having 7-22 carbon atoms; R₂ is H, an alkyl or hydroxyalkyl group with 1-6 carbon atoms; and m is an integer from 1 to 6, with an oxidant in the presence of a sterically hindered radical group and a co-catalyst, where the solvent is only water, and in the presence of an oxidant, the primary amide alcohol remains in the solid organic phase while the oxidant is distributed mainly into a liquid phase, wherein a base is further added to the reaction mixture.

EFFECT: improved method.

10 cl, 12 dwg, 11 ex