FIELD: medicine.
SUBSTANCE: for this purpose, the expression of markers of angiogenesis - CD34, apoptosis - p53, proliferative activity - Ki-67 is semiquantially evaluated in the tissue of patients with vulvar cancer by immunohistochemical method. At Ki-67 value within 80-90%, p53 value within 66.3-76.5%, CD34 value within 5.16-5.78% a short remission is predicted. At Ki-67 value within 7.6-9.8%, p53 value within 11.4-17%, CD34 value within 2.82-3.68% a long-term remission is predicted.
EFFECT: use of this invention allows to predict the occurrence of short or long-term remission in patients with vulvar cancer and, based on prognostic factors, assess the effectiveness of vulvar cancer treatment.
2 tbl, 2 ex
Title | Year | Author | Number |
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METHOD FOR PREDICTING COURSE OF TUMOUR PROCESS IN PATIENTS WITH VULVAR CANCER | 2015 |
|
RU2613119C1 |
METHOD OF PREDICTION OF RECURRENT VULVAR CANCER I AND II STAGE | 2015 |
|
RU2608508C1 |
METHOD FOR PREDICTION OF RECURRENT CARCINOMA OF VULVA | 2013 |
|
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METHOD FOR PREDICTION OF METASTASES IN PATIENTS WITH STOMACH CANCER | 2010 |
|
RU2445632C1 |
METHOD FOR PREDICTION OF RECURRENT VULVAR CANCER | 2013 |
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RU2517541C1 |
METHOD OF EVALUATING EFFICIENCY OF INTRAMURAL AUTOPLASMOCHEMICAL THERAPY OF URINE BLADDER CANCER | 2009 |
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METHOD FOR PREDICTION OF RECURRENT SOFT TISSUE SARCOMAS | 2013 |
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RU2532332C1 |
METHOD FOR DETERMINING AUTOHEMOCHEMOTHERAPY EFFECTIVENESS IN TREATING THE CASES OF CARCINOMA AFFECTING RECTOSIGMOID PORTION OF THE RECTUM AND SIGMOID COLON AND AUTOHEMOCHEMOTHERAPY COMBINED WITH ULTRAHIGH FREQUENCY HYPERTHERMIA IN TREATING THE CASES OF RECTAL CARCINOMA | 2001 |
|
RU2219553C2 |
METHOD FOR DETECTING EFFICIENCY OF ANTI-TUMOR THERAPY OF SKIN MELANOMAS | 2004 |
|
RU2280483C2 |
METHOD FOR PREDICTION OF RISK OF SQUAMOUS METAPLASIA IN RESPIRATORY BRONCHIAL EPITHELIUM WITH DETECTED ISOLATED BASAL CELL HYPERPLASIA | 2012 |
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RU2538642C2 |
Authors
Dates
2017-07-04—Published
2016-06-29—Filed