METHOD FOR TREATMENT OF INOPERABLE ASCTIC FORMS OF OVARIAN CANCER Russian patent published in 2017 - IPC A61K31/337 A61K31/282 A61K38/21 A61P35/00 

FIELD: medicine.

SUBSTANCE: for treatment of inoperable ascitic forms of ovarian cancer, the patients with inoperable stage III-IV of ovarian cancer, receive an abdominal cavity drainage after ascitic fluid removal, then recombinant interferon gamma is injected intraperitoneally, 500 thous. IU on day 1, 1 million IU on days 2, 3, 5, previously dissolved in 20 ml of 0.9% saline, on day 4, a course of polychemotherapy is carried out according to the scheme: paclitaxel 175 mg/m² IVFD, carboplatin (AUC 4-6) IVFD. 3 courses of immunochemotherapy are conducted with an interval of 21 days.

EFFECT: method allows to neutralise the toxic reactions of chemotherapy with a significant decrease in the tumor size with appearance of its mobility, which allows to perform treatment as the full scope of surgical intervention.

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