FIELD: medicine.
SUBSTANCE: level of IL-28B interferon-like cytokine is determined in the serum of pregnant women with a 6-11 week gestation period, by means of enzyme immunoassay. At IL-28B concentration above 261.4 pg/ml compared to the concentration established for a physiologically occurring pregnancy, a threat of miscarriage in the first trimester of gestation is projected. The invention provides improved accuracy of miscarriage threat prediction using an increase in the IL-28B cytokine concentration as a quantitative measure. The method is minimally invasive, convenient and simple to use, sufficiently informative and provides high reliability of the forecast.
EFFECT: use of this method will facilitate a more rapid and safe diagnosis of the threat of pregnancy termination of infectious genesis in the first trimester.
1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING OF MISCARRIAGE OF INFECTIOUS GENESIS AT EARLY STAGES OF GESTATION | 2016 |
|
RU2616902C1 |
| METHOD FOR PREDICTION OF EARLY MISCARRIAGE | 2012 |
|
RU2501017C1 |
| METHOD OF MISCARRIAGE PREDICTION ASSOCIATED WITH UROGENITAL INFECTION | 2007 |
|
RU2341799C1 |
| METHOD OF PREDICTING RISK OF MISCARRIAGE IN FIRST HALF OF PREGNANCY | 2014 |
|
RU2566728C2 |
| METHOD FOR PREDICTING GESTOSIS IN WOMEN AT THE RISK OF FAILED PREGNANCY | 2005 |
|
RU2296998C1 |
| METHOD OF PREDICTING DEVELOPMENT OF PLACENTAL INSUFFICIENCY IN SECOND HALF OF PREGNANCY IN WOMEN WITH THREAT OF MISCARRIAGE AT EARLY TERMS OF INFECTION GENESIS | 2014 |
|
RU2558795C1 |
| METHOD FOR ASSESSING THE RISK OF PRETERM DELIVERY IN WOMEN WITH HABITUAL MISCARRIAGE | 2018 |
|
RU2701109C1 |
| METHOD FOR PREDICTING THREATENING MISCARRIAGE DURING EARLY GESTATION PERIOD | 2005 |
|
RU2285926C2 |
| METHOD FOR PREDICTING GESTOSIS IN PREGNANT WOMEN WITH THE RISK FOR MISCARRIAGE OF INFECTIOUS GENESIS | 2003 |
|
RU2246255C2 |
| METHOD FOR PREDICTION OF PRETERM DELIVERY AT GESTATION PERIOD OF 24-34 WEEKS | 2017 |
|
RU2670672C1 |
